@snow My apologies. I read your comment wrong. In psychiatry, certain terms have very particular meanings. "Stimulant" refers to a particular class of medications, which we don't associate with antidepressants. Instead, we think of an antidepressant as "activating," which sounds like what you mean. Please correct me if I am mistaken. Antidepressants can affect patients in different ways. For example, common but paradoxical side effects associated with Cymbalta are insomnia and drowsiness. When starting a patient on an antidepressant, I always ask the patient to choose a time of day to take the medication, pay attention to whether the medication is activating or causes drowsiness, and then adjust the dosing schedule accordingly. In your case, I would recommend that you take Cymbalta in the morning due to its activating effects.