I remember reading and replying to your posts. I did a search, and I can't find your posts or my replies. Very odd. I'll do my best to recreate my reply.
I'm not sure what you define as low PSA. My oldest brother, who was 69 in November 2022, was diagnosed with stage 4 prostate cancer. He had not been having annual physicals with his GP, so we have no history of changes over time, but he had no symptoms, until he difficult peeing. His PSA at the time of testing was 200+ and his prostate was measured at 80cc in size. His Gleason score was 9 (5+4). After 2 years of treatment, with radiation, chemo, and hormone therapy, he is free of prostate cancer.
In mid-2023 my other brother, who was 66 years old, was also diagnosed with prostate cancer, his Gleason score was 7, and decided to wait on any treatment. His PSA score was 7, which his doctor's thought was BPH related. By March 2024 he got a biopsy, and they started treatment, with radiation, and hormone therapy. He is still on hormone therapy.
In February 2024, at the age of 60, my PSA was 2.0, my GP did the digital examination and didn't feel any. He felt my slightly elevated PSA was due to age related BPH. We agreed that I'd get my PSA checked again in August. When I did, my PSA 4.1. I told my GP about my updated family history with prostate cancer, and he agreed I should get an MRI and a PET-SCAN. I did, and it showed lesions on the left side.
That was September 2024, my PSA 6.0, my prostate 39cc. In October, I had a biopsy, which indicated a Gleason score of 9 (5+4). November 2024, I had surgery. The pathology report came back that there was no spread. I just had my first PSA test since surgery, with a result of 0.006.
As it has been explained to me, while you have a prostate, the PSA value is relative to the size of the prostate. The larger the prostate, the higher the PSA will likely report. Some men have prostates at 80 to 110cc, so their expect PSA is higher. In my opinion, the standard should be that any elevation of PSA should be followed up with an MRI, since imaging is far more definitive.
BTW - I'm going to direct message this to you, just in case it disappears again.
