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I am 63 yo female new to this site. I have been struggling with constipation for a long time due to opioid and other medications. I have severe spinal osteoarthritis, post 2 surgeries, thoracic spinal cyst (Srynx) Rheumatoid Arthritis and Fybromylagia. I also had hemorrhoidectomy in 2007 which may contribute to my issues. Relestor approved by medicare at a cost of $600 per month, which I cannot afford. I take Linzess daily and 4-5 Senna Plus each night. In addition, Relestor,as I can get samples from GI. I reserve Relestor for times when I have gone about 10 days without BM. Recently I have experienced bouts of incontinence. I am now afraid to leave house without a diaper. I have the loudest, foulest and unexpected gas without warning. I have been impacted on multiple occasions. I drink a minimum of 64 oz water daily, sometimes more due to dry mouth from all the meds. I walk a minimum of 2 miles most days with my pup, sometimes 4, depending on temperature. I am at my suggested BMI, eat low carb diet with lots of fruit and vegetables. I am so frustrated!! I know there are many people that are so worse off. My husband of 41 years is loving and supportive. When I finally poop, I can sit on toilet for 10 plus flushes over several hours and multiple times over next day and a half. I end up canceling appointments, I can’t leave house when I’m finally getting relief. Family gets frustrated if I cancel. They don’t know why I haven’t had this fixed!! It is depressing as they are unable to understand what they are not going through. On the outside I look fine. My insides not so much. Any thoughts would be appreciated from those who experience this difficult situation.